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RESEARCH PROJECTS

Our Current Focus

Scientist in the Lab
Embryonic Stem Cells

CHOLINE METABOLISM IN OSTEOARTHRITIS

By using cultured cells, mouse models and human specimens, we investigate how choline uptake, choline phosphorylation, and phospholipid remodeling mediate macrophage phenotype in osteoarthritis.

MECHANISMS THAT CONTROL METABOLIC REPROGRAMMING IN ACTIVATED MACROPHAGES

  • We investigate how mitochondria biogenesis and function shape macrophage phenotype. 

  • We study the interplay between metabolic adaptation and signal transduction in active macrophages.

  • We analyze metabolism-related protein modifications during macrophage activation. 

Research: Research
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